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In order to develop treatments, we need to fully understand what is going wrong in the cell. Genes related to pathways involved in the breakdown and transport of proteins within the cell, the so-called endosomal-lysosomal system, are increasingly being shown to play a role in the development of Parkinson’s disease. Our research focuses on the study of these aberrant pathways using the fruit fly, Drosophila melanogaster, as well as cellular models of disease.
Parkinson’s disease affects approximately 1 in 500 people in the UK and there is currently no cure.
Drosophila melanogaster
Incubating experimental samples
Drosophila under the microscope
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